Low dose of vitamin D not associated with depression benefits

- Last updated on GMT

Low dose of vitamin D not associated with depression benefits
A daily dose of 400 IU of vitamin D3 plus 1,000 mg of calcium was not associated with symptoms of depression, says a new study.

Data from 36,282 postmenopausal women participating in the Women’s Health Initiative indicated that two years of supplementation did not reduce antidepressant use or continuous depressive symptoms.

The study’s findings, published in the American Journal of Epidemiology​, are at odds with other studies that have reported an association between vitamin D levels and lower incidence of symptoms of depression.

“The findings do not support a relation between supplementation with 400 IU/day of vitamin D3 along with calcium and depression in older women,”​ wrote researchers led by Elizabeth Bertone-Johnson from the University of Massachusetts.

“Additional trials testing higher doses of vitamin D are needed to determine whether this nutrient may help prevent or treat depression.”

Data from 81,189 participants of the Women's Health Initiative (WHI) Observational Study published in the American Journal of Clinical Nutrition​ indicated that the prevalence of depressive symptoms was 21% lower for women with daily vitamin D intakes exceeding 800 International Units (IU) per day, compared with intakes of less than 100 IU per day.

Source: American Journal of Epidemiology
Published online ahead of print, doi:10.1093/aje/kwr482
“Vitamin D Supplementation and Depression in the Women’s Health Initiative Calcium and Vitamin D Trial”
Authors: E.R. Bertone-Johnson, S.I. Powers, L. Spangler, J. Larson, et al.

Related news

Show more

Related products

show more

Resveratrol – Revitalizing Cognitive Function

Resveratrol – Revitalizing Cognitive Function

Evolva | 29-Sep-2017 | Technical / White Paper

Cognitive decline is fast becoming the biggest concern of the 65+ population. A population which is set to reach 1.1 billion by 2030*.  · 80% of 60+ take...

Natural, slow-release caffeine by Lipofoods

Natural, slow-release caffeine by Lipofoods

Lipofoods, a Lubrizol Company | 25-Sep-2017 | Data Sheet

Lipofoods presents NEWCAFF™ microcapsules, a natural, slow-release caffeine with a clean non-bitter taste, ideal for sports and nutrition products targeting...


12 Reasons MenaQ7® is the Superior Vitamin K2

NattoPharma USA, Inc. | 11-Sep-2017 | Data Sheet

Vitamin K2 as MK-7 supplements are truly changing the face of global health, benefiting old and young alike. We know this because NattoPharma has single-handedly...

Related suppliers

Follow us


View more