Jim Roza on SophorOx for weight management

By Claudia Adrien

- Last updated on GMT

Related tags Obesity Weight loss Metabolic syndrome Body mass index

Jim Roza, chief scientific officer at Layn Natural Ingredients, spoke with NutraIngredients-USA at this year’s SupplySide West about SophorOx, a supplement that can assist in weight management.

SophorOx is a flavonoid extract from the buds of the Sophora japonica plant. Sophora japonica is commonly known as the Japanese pagoda tree. The flowers are harvested before they bloom, and they are used as source material for the product.

SophorOx has been clinically studied in humans to reduce oxidative stress.

“I think it's important for people understand that [it’s essential] to keep oxidative stress in check, by making sure you're getting plenty of antioxidants,” Roza said. “One of the problems is, as Americans, we don't eat a lot of fruits and vegetables. We don't want to eat a lot of green and leafy vegetables. We like a lot of processed foods. Well, you're not getting a lot of antioxidants from those types. And of course, we know that obesity is at epidemic proportions. I think there are some studies that show close to half the American population is at high risk of being overweight and obese.”

He added: “People who have high oxidative stress levels have a higher propensity to store more fat. I’m referring to white fat, not brown fat, which is less metabolically active and is more prone to give off inflammation. Now, when this inflammation occurs, what happens is it affects different bio pathways in the body that can lead to DNA mutation. It can affect the integrity of cell membranes, and it can lead to a number of different conditions that are deleterious to human health.”

In a clinical study by Layn, the use of SophorOx reduced waist circumference by one inch in the experimental group, whereas within the placebo group participants only reduced waist circumference by an eighth of an inch. Roza said these results were statistically significant.

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