Writing in Diabetes Metabolism Research and Reviews, scientists commissioned by Cargill report that the concentration of glucosamine in plasma following supplementation is several orders of magnitude below levels reported to impair glucose metabolism in vitro.
The review was welcomed by Cargill, which supplies the Regenasure glucosamine ingredient said to be suitable for vegetarians and those with shellfish allergies.
"Cargill is committed to the safety of its products," said Mark Christiansen, Acidulants product line manager for Cargill Corn Milling North America. "We felt it was important to investigate the on-going concern of glucosamine consumption related to diabetes. This review indicates that, at normal consumption levels, consumers can safely use glucosamine."
Source: Diabetes Metabolism Research and Reviews
2011, Volume 27, Pages 14-27, doi: 10.1002/dmrr.1150
“A comprehensive review of oral glucosamine use and effects on glucose metabolism in normal and diabetic individuals”
Authors: R. R. Simon, V. Marks, A. R. Leeds, J. W. Anderson