Technical / White Paper
Lactobacillus plantarum PPLP-217: Dossier on Safety, Efficacy and Regulatory Status
The L. plantarum PPLP-217 clinical dossier includes significant strain specific documentation for supporting health outcomes, as summarized below. Available data supporting L. plantarum PPLP-217 includes an infection surveillance study to assess the target area and unmet medical need, the safety, tolerance and long-term persistence/colonization of L. plantarum PPLP-217 in the neonatal gut, modulation of the gut microbiota upon administration of L. plantarum PPLP-217 and a randomized controlled trial of > 4,500 newborns in rural India showing efficacy in the prevention of sepsis and other infections. Additional clinical documentation supporting early life health outcomes, including prevention of stunting, is also summarized.
