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In vitro–in vivo Validation of Stimulatory Effect of Oat Ingredients on Lactobacilli
![In vitro–in vivo Validation of Stimulatory Effect of Oat Ingredients on Lactobacilli](/var/wrbm_gb_food_pharma/storage/images/_aliases/wrbm_product_file/publications/food-beverage-nutrition/nutraingredients-usa.com/product-innovations/in-vitro-in-vivo-validation-of-stimulatory-effect-of-oat-ingredients-on-lactobacilli/12382726-1-eng-GB/In-vitro-in-vivo-Validation-of-Stimulatory-Effect-of-Oat-Ingredients-on-Lactobacilli.jpg)
Findings of a recent study conducted by researchers of APC Microbiome Ireland showed significant benefit of utilizing a scientifically validated in vitro gut model (M-SHIME) prior to a human clinical trial. The in vitro analysis conducted by Duysburgh et al. (2020), reported a significant increase of Bifidobacterium and Lactobacillus levels in response to prebiotic oat treatment, confirming the validity of a human clinical trial. This resulted in a partnership with Atlantia Clinical Trials to further test the validity of prebiotics to stimulate Lactobacillaceae and Bifidobacteriaceae/ increasing propionate and butyrate production.