Technical / White Paper

In vitro–in vivo Validation of Stimulatory Effect of Oat Ingredients on Lactobacilli

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This Technical / White Paper has been written by Atlantia Clinical Trials , and any views and opinions expressed do not necessarily reflect those of www.nutraingredients-usa.com

In vitro–in vivo Validation of Stimulatory Effect of Oat Ingredients on Lactobacilli

Findings of a recent study conducted by researchers of APC Microbiome Ireland showed significant benefit of utilizing a scientifically validated in vitro gut model (M-SHIME) prior to a human clinical trial. The in vitro analysis conducted by Duysburgh et al. (2020), reported a significant increase of Bifidobacterium and Lactobacillus levels in response to prebiotic oat treatment, confirming the validity of a human clinical trial. This resulted in a partnership with Atlantia Clinical Trials to further test the validity of prebiotics to stimulate Lactobacillaceae and Bifidobacteriaceae/ increasing propionate and butyrate production.

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