Technical / White Paper

Formulator’s Handbook: Disintegration Mechanisms

Format: PDF file | Document type: Technical / White Paper

Formulator’s Handbook: Disintegration Mechanisms

Disintegration is the process in which tablets/granules break up in an aqueous environment, allowing the active ingredient to be released for dissolution. A disintegration aid added to a powder blend for direct compression tableting or encapsulation is called a disintegrant.

This handbook details topics including:

  • The Mechanisms Influencing Disintegration
  • Working With Disintegrants
  • How to Improve Disintegration Time
  • Effervescents
  • Fast Disintegrating Tablets
  • Excipients to Accelerate Disintegration

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