DE111® is a clinically studied strain of Bacillus subtilis that delivers benefits for digestive health, immune health, regularity and sports nutrition. More than 30 studies, including full genome sequencing, have been performed to confirm the safety and efficacy of Bacillus subtilis DE111. Bacillus subtilis has the ability to form spores that protect the microbes from harsh conditions until they enter an environment ripe for germination, such as the GI tract. Because DE111 remains viable under a wide temperature and pH range, the probiotic is ideal for use in supplements, foods and beverages.