Postbiotic L. gasseri CP2305 for mood, stress and sleep

As consumers of all ages become increasingly connected to their holistic wellbeing, emotional health support has come under the spotlight as a foundation of overall health.

Research shows that 75% of consumers recognize a link between mental and overall health. That this coincides at a time when lifestyles have never been busier is likely no coincidence.¹ According to research 73% of consumers report feelings of stress and 45% experience sleep problems nightly.¹ Stress and sleep are closely linked, with poor sleep linked to mood disorders, loss of productivity, and more serious health conditions.

With individuals juggling careers with family life and navigating the daily pressures these can bring, consumer demand for proven stress, mood, and sleep solutions is higher than ever.

Supplements and functional foods are increasingly emerging as solutions to support here. But there is a gap in the market: only 4% of global products have a sleep and stress function claim.¹

What ingredients can help bridge this shortfall?

With the growing interest in the gut microbiota and its interaction with the brain, the potential of biotics is well established for their ability to support a range of health needs. The microbiome is increasingly being researched for its potential to positively affect aspects of mood, stress, sleep, and overall human wellness.

Within this field, postbiotics are emerging as a promising area of innovation, thanks to their ability to impact the gut-brain axis and support a range of consumer needs, from metabolic health to digestive health, as well as stress, mood, and sleep.

Postbiotics: An evolving field

According to the International Scientific Association for Probiotics and Prebiotics (ISAPP), postbiotics are defined as a “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”.

They exert their effects through a range of mechanisms: modulating the immune system; enhancing gut barrier function; suppressing pathogenic bacteria; balancing the gut microbiota; and acting as antioxidants or anti-inflammatory agents.

As the science continues to evidence the positive impacts that postbiotics can bring, they have been gaining market traction. In 2021, the global postbiotic market was valued at $1.6 billion and is expected to reach $3 billion by 2031.²

For formulators, postbiotics offer flexibility for differentiated foods, beverages, dietary supplements, and pet nutrition. Unlike live probiotics, postbiotics are less susceptible to environmental factors such as heat and pH, offering enhanced stability and shelf life in end use.

And as the body of research into postbiotics grows, so does consumer interest and confidence, with research showing that 38% of US consumers are interested in taking postbiotics.³

A ‘one-of-a-kind’ postbiotic

As evolving needs of consumers are being met through novel postbiotics and innovative functional foods and beverages and food supplements, Lactobacillus gasseri CP2305 is positioned as a breakthrough postbiotic formula which provides both mood, stress, and sleep support – the first strain that can affect three mood states in a single ingredient.

The unique postbiotic is backed by eight clinical trials and has been shown to help reduce stress, improve mood, and support better sleep efficiency. ADM’s newest microbiome solution works by leveraging the potential of the gut-brain axis by modulating the gut microbiome, maintaining levels of beneficial Bifidobacteria in individuals under stressful conditions. With demand rising for more ways to relieve stress and its associated negative impacts, L. gasseri CP2305 is the ideal postbiotic solution with clinical evidence of stress reduction support.⁴

Gold standard: Backed by science

Stress and mood support Clinical studies show that 20mg/10B cells daily of L. gasseri CP2305 may support emotional wellbeing, reduced stress, and improved self-reported assessments of mental wellbeing.⁵

The postbiotic’s positive effects extend to women’s health and exercise recovery. A daily supplement of L. gasseri CP2305 may support positive physiological changes in women experiencing menopause and reduced anxiety in young women experiencing premenstrual symptoms. It can also promote better sleep efficiency.⁶ Exploratory research suggests that supplementing a diet with L. gasseri CP2305 may be associated with reduced time to fall asleep and improved total duration of sleep.⁷

The postbiotic’s positive effects extend to women’s health and exercise recovery. A daily supplement of L. gasseri CP2305 may support positive physiological and emotional changes in women experiencing menopause as well as support for positive moods, reduced stress and anxiety, improved skin appearance, and reduced occasional constipation in young women experiencing premenstrual symptoms. Clinical study evidence shows that supplementing with L. gasseri CP2305 may support reduced levels of stress and occasional fatigue associated with exercise.

Flexible formulation capabilities

As a heat-stable postbiotic, L. gasseri CP2305 offers limitless possibilities for applications from traditional supplements and gummies to a range of functional foods. It provides more stability and a longer shelf life than traditional lactic acid bacteria probiotics, enabling it to retain efficacy for optimal performance.

It is also QPS/GRAS, non-GMO, gluten-free, and lactose-free, making it suitable for consumers with dietary and lifestyle restrictions.

Find out more - register for Spotlight On

Join us for a Spotlight On Postbiotics: The Future of Stress, Mood, Sleep & Women’s Health on October 9,, 2025 to discover how the microbiome is reshaping the future of mental wellbeing and the potential of L. gasseri CP2305.

Experts from ADM and Lumina Intelligence will present the latest consumer insights into the growing interest in postbiotics as powerful tools for managing stress, improving mood, and enhancing sleep quality, and cover the various health states that are driving the market.

From ever-growing research around the gut-brain axis to increasing focus on women’s health, along with overall whole-body health, ADM will showcase science-backed ingredients that manufacturers can leverage to address current and emerging consumer demands.

You’ll also hear from a renowned independent scientific expert who will break down the cutting-edge research behind L. gasseri CP2305.

This broadcast event will equip you with the insights and tools to navigate and lead the future of holistic mental wellbeing. Don’t miss this opportunity to stay one step ahead on one of the most compelling intersections in health – the gut-brain connection.

Register here for Spotlight On Postbiotics: The Future of Stress, Mood, and Sleep.

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