Clear Probiotics launches synbiotic to avert herpes outbreak

By Danielle Masterson

- Last updated on GMT

© Getty Images privetik
© Getty Images privetik

Related tags Probiotic Prebiotic synbiotics Gut bacteria LGG

Clear Probiotics recently debuted a probiotic and prebiotic formula that aims to prevent lip outbreaks and alleviate associated issues.

More than 3.7 billion people worldwide and 320 million Americans suffer from lip outbreaks due to symptoms associated with herpes simplex virus type 1 (HSV-1), according to the World Health Organization. 

The company said that while a number of treatments such as antivirals, topicals, vitamin C, and zinc are available to promote healing, Clear Probiotics aids in outbreak prevention. 

“Unlike other treatments currently available that are designed to relieve lip pain and promote healing once an outbreak has happened, Clear Probiotics is specifically formulated to aid in preventing lip flare-ups and outbreaks,”​ said Greg Brauser, CEO and founder of Clear Probiotics.

The mouth-gut axis

About 70% of the immune system lives in the gut, so a healthy digestive system is essential for alleviating lip outbreaks, and promoting health overall. 


The Clear Probiotics formulation contains Lactobacillus Rhamnosus GG​ (LGG) as well as a prebiotic developed specifically for alleviating lip issues.

Kristin Kirkpatrick, MS, RDN, Scientific Advisor for Clear Probiotics, told NutraIngredients-USA​ that the secret’s in the strain: “The LGG strain has been extensively studied for its implications in gut health. Specifically, the LGG strain has been found to promote beneficial gut bacteria and may have beneficial implications as a co-treatment in lip outbreaks through its anti-viral components as well as microphage activation,” ​explained Kirkpatrick. “The formula has been specifically studied on the virus that causes lip outbreaks. This clinical trial​ covers the research done to show its impact on alleviating lip outbreaks through better gut health. ​Lactobacillus rhamnosus and fructooligosaccharides (both contained in Clear Probiotics) significantly decreased both the occurrence and the incidence of herpes labialis lesions after stimulation with ultraviolet radiation in a population with recurrent herpes labialis.”

Kirkpatrick added that clinical trials have demonstrated that Lactobacillus rhamnosus​ and fructooligosaccharides​ significantly decreased the occurrence and incidence of herpes labialis lesions after stimulation with ultraviolet radiation in a population with recurrent herpes labialis.


With more health-conscious consumers emerging, the nutraceutical industry is uniquely positioned to lead in this crisis. Immune products in particular are experiencing a surge, with suppliers, manufacturers and retailers reporting record growth in the category in recent months. 

Data Bridge Market Research recently released the report US HSV-1 Treatment Market, ​which found that the treatment market is expected to reach over one billion dollars in the United States by 2027, up from $475.15 million reported in 2019. Additionally, the cold sores segment was dominating the market with a market share of 84.5% in 2020 and growing with the CAGR of 11.6% in the forecast period of 2020 to 2027.

“From what we have seen since launching Clear Probiotics, along with what has recently been reported in a Global Outlook and Forecast on the Probiotics Supplements Market for 2020-2025, the market for immunity-oriented probiotics supplements is experiencing a surge in demand that is expected to continue to spike in the third and fourth quarters of 2020. Additionally, manufacturers who have maintained their facility operations have taken steps to monitor their logistics and maintain the supply of materials to ensure consistent product delivery,”​ said Brauser. 

With the industry primed for growth he said he is optimistic about the role Clear Probiotics will play: “With the latest market industry research demonstrating a consumer need for a probiotic such as ours, there is a large opportunity for growth in this category that we anticipate playing a big role in it.”

With such an encouraging forecast, Brauser told NutraIngredients-USA​ that the company plans  to launch other probiotics that target specific populations.

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