‘Next gen’ probiotics: Chr. Hansen adds 100 new strain development library

By Nathan Gray contact

- Last updated on GMT

‘Next gen’ probiotics: Chr. Hansen adds 100 new strain development library

Related tags: Bacteria

Danish bioscience firm Chr. Hansen says 100 new strains added to its library could help development of new commercial probiotics for a range of metabolic, immune, and digestive health issues.

A partnership between Chr. Hansen and three academic institutes –Rowett Institute, Wageningen University and University of Groningen – has led to the addition of new strains into the Chr Hansen library.

“From over 1000 recently screened strains from the human microbiome, we have identified a subset of 100 that can be developed for a broad array of health indications associated with gastrointestinal, immune and metabolic health,” said Johan van Hylckama Vlieg, VP of microbiome and human health innovation.

The Danish firm said adding a well-documented collection of novel strains from microbiome species, such as Faecalibacterium prausnitzii​ and Eubacterium hallii​ that are widely regarded as primary candidates for next generation probiotics, is a major milestone.

The newly added strains will be used both for Chr. Hansen’s internal innovation efforts, and made available to external partners and customers looking to accelerate development of next generation probiotics, said the company.

“Now we have a shortlisted selection of strains that we believe will be of major interest to innovators in the microbiome space, who are looking to develop next generation of probiotics and live biotherapeutics. It is our goal to help our customers and partners move these new documented strains from the lab to the clinic,”​ commented Chr. Hansen senior scientist Gemma Henderson.

“Our safety assessment includes screening for absence of antibiotic resistance and virulence factors. We also looked for their ability to grow in industrial media and sensitivity to oxygen. And we also screened for the ability of strains to impact the immune system,”​ she added.

However, the company noted that developing these sort of ‘microbiome strains’ as next generation probiotics for food and supplement applications presents unique challenges. For example, many of the relevant species have no history of commercialisation and were until recently described as difficult to cultivate. This means that many strains require new techniques for cultivation and production.

Related topics: Suppliers, Probiotics & prebiotics

Related news

Show more

Related products

show more

It’s time for HRB – A lifelong health partner

It’s time for HRB – A lifelong health partner

Morinaga Milk Industry Co., Ltd. | 19-Nov-2020 | Technical / White Paper

Consumer awareness of the importance of choosing the right probiotics that possess extensive clinical efficacy to address fundamental health problems (e.g.,...

Next-wave sports nutrition innovation today

Next-wave sports nutrition innovation today

ADM | 28-Oct-2020 | Technical / White Paper

Today’s consumers are passionate about embracing health in many aspects of their lives, starting with customizing their nutrition. Rooted in proprietary...

Biotis™ - Solutions for a good gut feeling

Biotis™ - Solutions for a good gut feeling

FrieslandCampina Ingredients | 07-Oct-2020 | Product Brochure

Discover our range of GOS (galacto-oligosaccharides) with scientifically proven effects to significantly increase levels of ‘friendly bacteria’ in the...

Related suppliers

Follow us

Products

View more

Webinars