Fibersol-2 may boost satiety: Human RCT data


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Fibersol-2 may boost satiety: Human RCT data

Related tags: Dietary fiber

Adding soluble fiber to a tea that is consumed along with a meal can increase satiety hormones and decrease hunger in health men and women, say results of randomized, double-blind, placebo-controlled crossover study.

Ten grams of the commercial Fibersol-2 ingredient in a tea was associated with significant increases in levels of the appetite-regulating hormones, PYY and GLP-1, report researchers from Iowa State University and Archer Daniels Midland Company.

“Not all dietary fiber products have the same effects on satiety,” ​they wrote in Nutrition Research​. “This study is one of the most comprehensive assessments to date of postprandial satiety produced by a functional dietary fiber, as seen in subjective measures and using an extensive panel of satiety factors.”

The ingredient

Fibersol-2 is a digestion-resistant maltodextrin commercialized in a joint venture between ADM and Matsutani LLC.

The soluble dietary fiber be added to dietary supplements and a wide range of foods and beverages, without adding unwanted flavor, texture or color, says the company. The ingredient has been recognized as GRAS (generally recognized as safe) by the FDA and is Kosher and Pareve.

Study details

Led by Zhong Ye from Iowa State, the researchers recruited nine men and 10 women to participate in their study. The volunteers were asked to consume a standardized meal and were also given a tea containing 0, 5, or 10 g of Fibersol-2. Blood samples were taken at the start of the experiment and then every 30 minutes for four hours.

Results showed that the 10 gram dose of Fibersol-2 was associated with significant delays in hunger and increased satiety 1.5 to 2 hours after ingestion, but no such effects were observed for the lower dose or the control interventions.

Fibersol-2 data
Plasma satiety hormone measurements for PYY [A] and GLP-1 [B]vs time for 0, 5 g, and 10 g Fibersol-2. Source: Nutrition Research, doi: 10.1016/j.nutres.2015.03.004, Elsevier

Analysis of the blood samples indicated that PYY and GLP-1 significantly increased by the ingestion of meal with tea containing 10 g Fibersol-2, but no such increases were observed in the 0 or 5 g Fibersol-2 interventions.

“Satiety factors work in concert to stimulate and decrease feeding depending on metabolic needs,” ​wrote the researchers. “Fibersol-2 significantly increased the satiety hormones PYY and GLP-1, and study participants perceived postprandial increases in satiety.

“Prevention or mitigation of obesity using such food ingredients as Fibersol-2 will require studies of long-term effects on these satiety factors.”

Source: Nutrition Research
Published online ahead of print, doi: 10.1016/j.nutres.2015.03.004
“Soluble dietary fiber (Fibersol-2) decreased hunger and increased satiety hormones in humans when ingested with a meal”
Authors: Z. Ye, V. Arumugam, E. Haugabrooks, P. Williamson, S. Hendrich

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