Kyowa Hakko granted US patent for L-Citrulline and L-Arginine Combination for blood flow benefits

Kyowa Hakko granted US patent for L-Citrulline and L-Arginine Combination for blood flow benefits

Related tags Kyowa hakko usa Amino acid Kyowa hakko

The US Patent and Trademark Office has granted a patent to Kyowa Hakko for the combination of the amino acids L-citrulline and L-arginine for boosting blood L-arginine levels and increasing blood flow.

US Patent number 8,609,735​ is titled, “Rapid-acting, blood-arginine-level-increasable oral preparation comprising citrulline and arginine”.

L-arginine is an amino acid critical to the production of the potent vasodilator nitric oxide (NO) in the body, which can regulate and improve blood circulation. L-Citrulline is a major precursor to L-Arginine and has been shown in other studies to increase L-Arginine levels, and thus improve NO production.

“We measured blood L- Arginine levels and Nitric Oxide levels 40 minutes and 60 minutes after amino acids administration,”​ said Ryusuke Nakagiri, Senior Director of Strategic Science at Kyowa Hakko USA. “At both time points, the combination of L-Citrulline and L-Arginine had a better effect than the single amino acids.”

Both ingredients are manufactured at the company’s Cape Girardeau, Missouri, facility.

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