Science in brief

Folic acid supplements fail to boost mood in young people

Folic acid supplements fail to boost mood in young people

Related tags Folic acid

Dietary supplements containing folic acid did not improve influence the incidence of mood disorder in young people with an increased familial risk of the condition, says a new study.

Data from epidemiological studies have suggested that low folate levels may increase the risk of depressive symptomatology in the general population leading to the hypothesis that folic acid supplements may influence mood.

However, in a randomized, double blind, parallel group, placebo-controlled trial with 112 young people with an increased familial risk of mood disorder, folic acid supplements at a dose of 2.5 milligrams per day did not significantly affect the incidence of mood disorder.

Data published in the Journal of Affective Disorders​indicated that, “there was post-hoc evidence that folic acid delayed the time to onset of mood disorder in those participants who became unwell.

“In addition, the mood disorders in the folate treated participants, when they occurred, tended to be clinically milder.”

Scientists from Oxford University in England noted that their study was limited by not recruiting the targeted number of subjects, and because the rate of onset of mood disorders was lower than they expected.

“Thus we cannot exclude that a larger participant sample or different experimental design would have shown a significant beneficial effect of folate prophylaxis.”

Source: Journal of Affective Disorders
Volume 167, Pages 306-11, doi: 10.1016/j.jad.2014.06.011
“Folic acid supplementation for prevention of mood disorders in young people at familial risk: A randomised, double blind, placebo controlled trial”
Authors: Sharpley AL, Hockney R, McPeake L, Geddes JR, Cowen PJ.

Related news

Show more

Related products

show more

Formulate for women’s health – formulate empowerment

Formulate for women’s health – formulate empowerment

Content provided by Verdure Sciences | 26-Mar-2024 | Product Brochure

Women’s health trends are mirroring bigger conversations of empowerment and wellbeing. Within the women’s health category, upticks in areas of lean muscle...

LocVita® D3: Tailored Formulas & Beadlet Solutions

LocVita® D3: Tailored Formulas & Beadlet Solutions

Content provided by INNOBIO Corporation Limited | 11-Mar-2024 | White Paper

LocVita® Vegan Vitamin D3 delivers specially formulated options that are sugar-free and organic, designed to accommodate various dietary preferences and...

Go Beyond the Ordinary: Cognitive Health-BacoMind

Go Beyond the Ordinary: Cognitive Health-BacoMind

Content provided by Natural Remedies Private Limited | 27-Feb-2024 | White Paper

Experience the potency of BacoMind®, the #1 branded bacopa with 9 key bioactives for unparalleled cognitive support.

Related suppliers

Follow us

Products

View more

Webinars