Writing in PLoS ONE, the researchers also report that the berry-enriched protein matrices – the Nutrasorb technology previously covered by NutraIngredients-USA – enhanced the absorption of polyphenols in the large intestine, a result that runs contrary to many
“Burn fat while you sleep is a great message,” said Mary Ann Lila, PhD, director of the North Carolina State University Plants for Human Health Institute (PHHI) in a statement.
“We showed that the metabolism is stimulated by exercise, but we saw fatty acid oxidation and ketogenesis with more ketones at 14 hours post exercise in the treatment group. The placebo group went back to normal levels.”
The study is said to be the “first really strong evidence of bioavailability” of the Nutrasorb, said Lila, and builds on data from animal and lab studies.
The Nutrasorb technology has been developed by Lila and scientists at Rutgers University. As reported previously by us, the bioactive sorption technology works by impregnating soybean flour with antioxidant-rich berry or fruit extracts.
Rutgers University researchers published their findings in Food Chemistry (doi: 10.1016/j.foodchem.2011.09.103) that indicated that 1.4 grams of blueberry-impregnated defatted soybean flour provides the same polyphenol content as 73 grams of fresh blueberries.
Similarly, 1 gram of the cranberry-impregnated defatted soybean flour has the equivalent polyphenol content as three 8 ounce glasses of cranberry juice.
The new study, a collaboration with David Nieman, DrPH, from the Appalachian State University (ASU) and Nicholas Gillitt, PhD, from the Dole Nutrition Research Laboratory is said to be an important step forward in the development of the technology, said the NC Research Campus.
The researchers recruited 35 long-distance runners aged between 19 and 45 to participate in their double-blind randomized trial. Participants were randomly assigned to receive either 40 grams per day of the polyphenol soy protein complex (2,136 mg/d gallic acid equivalents) or placebo (N = 18) for 17 days. At day 14, the researchers introduced a three day running period.
“Following intensive and prolonged running, athletes experience transient inflammation, oxidative stress and immune dysfunction,” explained Nieman.
“Metabolomics, a new technology that simultaneously measures changes in hundreds of metabolites, showed that the majority of the polyphenols went to the colon, where the bacteria broke them down into smaller phenolics.
“The intense exercise increased gut permeability, promoting the transfer of phenolics into the body in much higher amounts then before the exercise.”
The researchers also found that the runners in Nutrasorb group showed a longer spike in their metabolism after exercise.
"The daily polyphenol dose used in this study was equivalent to 2,136 mg/d gallic acid equivalents," explained the researchers in PLoS One. "This is substantially above the typical adult intake, but larger doses for a longer period of time may prove to be more efficacious. Subjects in the PSPC group showed an elevation in fat oxidation and ketogenesis 14-h post-exercise."
Source: PLoS ONE
8(8): e72215. doi:10.1371/journal.pone.0072215
“Influence of a Polyphenol-Enriched Protein Powder on Exercise-Induced Inflammation and Oxidative Stress in Athletes: A Randomized Trial Using a Metabolomics Approach”
Authors: D.C. Nieman, N.D. Gillitt, A.M. Knab, R.A. Shanely, K.L. Pappan, F. Jin, M.A. Lila