Beta-glucan structure determines immune response: Study
Published in Blood, the studies employed Biothera soluble and particulate beta-glucans which were found to behave differently in mediating immune modulatory effects such as T cell activation.
“These data demonstrate how different beta-glucan structures affect immunomodulatory mechanisms,” said principal investigator Jun Yan, MD, PhD, of the University of Louisville School of Medicine.
Source:
Blood
2011 117:6825-6836; doi:10.1182/blood-2011-02-339812
‘Differential Pathways Regulating Innate and Adaptive Anti-tumor Immune Responses by Particulate and Soluble Yeast-derivedβ-Glucans’
Authors: Chunjian Qi, Yihua Cai, Lacey Gunn, Chuanlin Ding, Bing Li, Goetz Kloecker, Keqing Qian, John Vasilakos, Shinobu Saijo, Yoichiro Iwakura, John R. Yannelli, Jun Yan
