The third most read science article of 2014 on NutraIngredients-USA concerned mitochondria and aging.
It’s already well known that the function of mitochondria declines with age, while aging is a known risk factor for a number of common age-related and neurodegenerative disorders. This led to the proposition that secondary mitochondrial dysfunction may lead to degenerative diseases.
A role for oxidative stress has been proposed to promote mitochondrial dysfunction, leading some researchers to examine if antioxidants such as CoQ10, and vitamins C and E may play a role.
Nicotinamide riboside (NR), a no-flush version of niacin (vitamin B3), has also been garnering a lot of interest, and researchers from the University of Helsinki (Finland), École Polytechnique Fédérale de Lausanne (Switzerland), the University of Eastern Finland, and the Metabolomics Unit at the Institute for Molecular Medicine Finland (FIMM) reported that oral supplementation with NR “resulted in a remarkable induction of mitochondrial biogenesis and oxidative metabolism, with an increase in mitochondrial mass, […] and respiratory chain protein amounts in the muscle”.
We’ll continue to watch this cutting edge science closely…