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ENI builds science for whole grape extract with RCT data

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Related tags: United states patent and trademark office

ENI builds science for whole grape extract with RCT data
An extract from whole grapes may improve cholesterol levels, says a new study from Ethical Naturals Inc. (ENI) and KGK Synergize (Canada).

Results of a randomized, double-blind, placebo-controlled clinical study are said to indicate that ENI’s patented whole grape extract may increase HDL-cholesterol and decrease the ratio of total cholesterol to HDL-cholesterol in people with pre-hypertension, overweight, and/or pre-diabetes.

Cal Bewicke, President of ENI, said the study “scientifically validates the health benefits associated with products concentrated from whole grapes”​.

Bewicke told NutraIngredients-USA that the trial data has been submitted for publication in peer reviewed journal. NutraIngredients-USA has not seen the full data.

The ingredient

The US Patent and Trademark Office granted a patent in 2011 to ENI for the ingredient (U.S. Patent 7,959,963), and the ingredient is patent-pending in China and the European Union, said ENI. It is marketed under the brand names ORAC-15M and VinCare and it is standardized to contain 80% grape polyphenols with an ORAC Value of 15,000 micromolesTE/gram. The branded ingredients are GRAS affirmed, added the company.

In addition to the potential cholesterol benefits, six weeks of supplementation with the ingredient at a dose of 350 milligrams per day was also associated with improvements in key biomarkers reflecting oxidative stress, such as 8-isoprostane levels. 

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