Vitamin E status may be reliable biomarker for Alzheimer’s: Study

By Nathan Gray

- Last updated on GMT

Related tags Magnetic resonance imaging Alzheimer's disease Vitamin e

Vitamin E status may be reliable biomarker for Alzheimer’s: Study
Screening levels of vitamin E in the blood could help to improve the diagnosis of Alzheimer’s Disease, according to new research that suggests the vitamin may also aid in protection.

 

The study, published in the Journal of Internal Medicine​, evaluated the use of magnetic resonance imaging (MRI) and measures of plasma levels of vitamin E forms - including all eight natural vitamin E congeners (four tocopherols and four tocotrienols) - in differentiating individuals with Alzheimer's disease (AD) and mild cognitive impairment (MCI) from cognitively intact control (CTL) subjects.

Consistent with previous research findings, the new study – led by Francesca Mangialasche from the Karolinska Institutet, Sweden – reports that both AD and MCI patients had lower blood plasma levels of different vitamin E isomers, compared to CTL subjects.

“Plasma levels of tocopherols and tocotrienols together with automated MRI measures can help to differentiate AD and MCI patients from CTL subjects, and to prospectively predict MCI conversion into AD,”​ said Mangialasche and her colleagues.

“Our results suggest the potential role of nutritional biomarkers detected in plasma-tocopherols and tocotrienols-as indirect indicators of AD pathology, and the utility of a multimodality approach,”​ they concluded.

The study’s findings were welcomed by WH Leong, vice president of Carotech Inc, who commented that the study also shows that alpha and gamma-tocotrienol, as well as gamma-tocopherol are the most important vitamin E forms in differentiating AD and MCI cases from controls.

“It is encouraging to find consistent and positive research results supporting the importance of full spectrum vitamin E (d-mixed tocotrienols + d-mixed tocopherols or E-Complete) in cognitive improvement,”​ said Leong.

“This European study adds further to the evidence that increased levels of full spectrum vitamin E in the plasma is beneficial for improvement of cognitive functions especially in elderly,”​ he added.

Related topics Research Cognitive function

Related news

Show more

Related products

show more

Go Beyond the Ordinary: Cognitive Health-BacoMind

Go Beyond the Ordinary: Cognitive Health-BacoMind

Content provided by Natural Remedies Private Limited | 27-Feb-2024 | White Paper

Experience the potency of BacoMind®, the #1 branded bacopa with 9 key bioactives for unparalleled cognitive support.

Nootropics Report 2.0: Brain Health Insights

Nootropics Report 2.0: Brain Health Insights

Content provided by dsm-firmenich | 22-Feb-2024 | Insight Guide

The brain health market is constantly growing and evolving, with more consumers looking for innovative ways to support total mind and body wellness.

Krill oil supports six key areas of healthy aging

Krill oil supports six key areas of healthy aging

Content provided by Aker BioMarine | 14-Feb-2024 | White Paper

The global population is getting older—according to WHO by 2050 the world’s population over 60 years will double and the population above 80 years will...

Consumers' growing demand for Omegas

Consumers' growing demand for Omegas

Content provided by Fruit d'Or | 13-Feb-2024 | White Paper

Consumers are increasingly interested in the benefits of omegas supplements. According to forecasts for 2023–2030, the global omega-3 market is expected...

Related suppliers

Follow us

Products

View more

Webinars